1. 1 phage target cells (sometimeswith their unwitting help)
  2. 2 their tail fibers recognizeand dock to their target cell
  3. 3 their tails (contractile or not)inject the phages genome
  4. 4 the genome directs the cells machinery tomake many copies of components
  5. 5 once the components assemble,the new phage make their exit
  6. 6 ...sometimes in dramatic style

Summary

Concept Check Questions

• Why are phage not considered a life form?

• Which macromolecule makes up the phage capsid?

• What structure do phage use to recognize their targets?

• Which bacterial structure is related to the phage tail?

Further Reading

• Keen (2015). A century of phage research: Bacteriophages and the shaping of modern biology [93].

• Prangishvili et al. (2017). The enigmatic archaeal virosphere [94].

• Rohwer et al. (2014). Life in Our Phage World [91].